Pseudouridine 5'-triphosphate (trisodium) solution (100mM)

CAT:

804-HY-141567A

Size:

5.5 mg

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UNSPSC Description: Pseudouridine-5’-triphosphate (Pseudo-UTP) trisodium solution (100mM) is one of the most commonly used modified nucleoside for the polymerase-mediated synthesis of RNA molecules. Compared with uridine-containing unmodified mRNAs, the application of pseudouridine-containing modified mRNAs exhibits better nuclease stability, immunogenicity, and translational properties[1]..
Target Antigen: DNA/RNA Synthesis
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Others
Assay Protocol: https://www.medchemexpress.com/pseudouridine-5-triphosphate-trisodium.html
Purity: 98.0
Solubility: 10 mM in DMSO
Smiles: O=P(O)(O[Na])OP(OP(OC[C@H]1O[C@@H](C(C(N2)=O)=CNC2=O)[C@H](O)[C@@H]1O)(O[Na])=O)(O[Na])=O
Molecular Weight: 550.09
References & Citations: [1]Muthian Shanmugasundaram, et al. An Efficient Protection-Free One-Pot Chemical Synthesis of Modified Nucleoside-5'-Triphosphates. Nucleosides Nucleotides Nucleic Acids. 2016 Jul 2;35(7):356-62.
Shipping Conditions: Blue Ice
Storage Conditions: Solution, -20°C, 2 years
Clinical Information: No Development Reported

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