Pseudouridine 5'-triphosphate (trisodium) solution (100mM)

Pseudouridine 5'-triphosphate (trisodium) solution (100mM)

• UNSPSC Description: Pseudouridine-5’-triphosphate (Pseudo-UTP) trisodium solution (100mM) is one of the most commonly used modified nucleoside for the polymerase-mediated synthesis of RNA molecules. Compared with uridine-containing unmodified mRNAs, the application of pseudouridine-containing modified mRNAs exhibits better nuclease stability, immunogenicity, and translational properties[1]..
• Target Antigen: DNA/RNA Synthesis
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/pseudouridine-5-triphosphate-trisodium.html
• Purity: 98.0
• Solubility: 10 mM in DMSO
• Smiles: O=P(O)(O[Na])OP(OP(OC[C@H]1O[C@@H](C(C(N2)=O)=CNC2=O)[C@H](O)[C@@H]1O)(O[Na])=O)(O[Na])=O
• Molecular Weight: 550.09
• References & Citations: [1]Muthian Shanmugasundaram, et al. An Efficient Protection-Free One-Pot Chemical Synthesis of Modified Nucleoside-5'-Triphosphates. Nucleosides Nucleotides Nucleic Acids. 2016 Jul 2;35(7):356-62.
• Shipping Conditions: Blue Ice
• Storage Conditions: Solution, -20°C, 2 years
• Clinical Information: No Development Reported