M-PEG12-OH

• Description :

  M-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [2].

• UNSPSC :

  12352203

• Hazard Statement :

  H315, H319

• Target :

  ADC Linker; PROTAC Linkers

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/m-peg12-oh.html

• Purity :

  99.59

• Solubility :

  10 mM in DMSO

• Smiles :

  COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

• Molecular Formula :

  C25H52O13

• Molecular Weight :

  560.67

• Precautions :

  H315, H319

• References & Citations :

  [1]Kachbi-Khelfallah S, et al. Towards potential nanoparticle contrast agents: Synthesis of new functionalized PEG bisphosphonates. Beilstein J Org Chem. 2016 Jul 4;12:1366-71.|[2]Hamura, Mika, et al. Branched monodispersed polyethylene glycol, intermediate, and method for producing same. WO 2019181984 A1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Non-cleavable Linker; PEG Linkers

• CAS Number :

  [2050595-03-2]