TCO-amine
CAT:
804-HY-141176
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TCO-amine
- CAS Number: 1609736-43-7
- UNSPSC Description: TCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. TCO-amine is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
- Target Antigen: PROTAC Linkers
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tco-amine.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(OC1CC/C=C\CCC1)NCCCN
- Molecular Weight: 226.32
- References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported