(S)-TCO-PEG3-amine

(S)-TCO-PEG3-amine

• UNSPSC Description: (S)-TCO-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. (S)-TCO-PEG3-amine is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/s-tco-peg3-amine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(O[C@H]1CCC/C([H])=C/CC1)NCCOCCOCCOCCN
• Molecular Weight: 344.45
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported