1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane

• UNSPSC Description:

  1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/1-3-bis-carboxyethoxy-2-2-bis-carboxyethoxy-propane.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(CCOCC(COCCC(O)=O)(COCCC(O)=O)COCCC(O)=O)O

• Molecular Weight:

  424.40

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Clinical Information:

  No Development Reported

• CAS Number:

  35638-19-8