Diketone-PEG12-Biotin

• UNSPSC Description:

  Diketone-PEG12-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/diketone-peg12-biotin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(NC1=CC=C(CCC(CC(C)=O)=O)C=C1)=O)CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O

• Molecular Weight:

  1031.26

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported