Boc-Aminooxy-PEG1-azide

• UNSPSC Description:

  Boc-Aminooxy-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-Aminooxy-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/boc-aminooxy-peg1-azide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OC(C)(C)C)NOCCOCCN=[N+]=[N-]

• Molecular Weight:

  246.26

• References & Citations:

  [1]Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2100306-67-8