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Amino-PEG6-Thalidomide

CAT: 0804-HY-140240Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-140240Size:1 Each
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Description
Amino-PEG6-Thalidomide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/amino-peg6-thalidomide.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2C(N(CCOCCOCCOCCOCCOCCOCCN)C(CC2)=O)=O)C(C3=CC=CC=C31)=O
Molecular Formula
C27H39N3O10
Molecular Weight
565.61
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

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