Amino-PEG6-Thalidomide

• Description :

  Amino-PEG6-Thalidomide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Autophagy; PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/amino-peg6-thalidomide.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N(C2C(N(CCOCCOCCOCCOCCOCCOCCN)C(CC2)=O)=O)C(C3=CC=CC=C31)=O

• Molecular Formula :

  C27H39N3O10

• Molecular Weight :

  565.61

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Cereblon