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FPI-1465

CAT: 0804-HY-139744Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139744Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FPI-1465 acts a dual inhibitor of serine-β-Lactamases and Penicillin-binding proteins (PBPs) .FPI-1465 inhibits PBP2 (IC50=1.0 µg/mL) . FPI-1465 exhibits activity against β-lactamase CTX-M-15 and OXA-48 with Kds of 0.011 and 5.3 µM, respectively[1].
CAS Number
1452458-70-6
UNSPSC
12352005
Target
Bacterial; Beta-lactamase; Penicillin-binding protein (PBP)
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fpi-1465.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1[N@@]2C(N([C@H](CC1)C2)OS(=O)(O)=O)=O)NO[C@@H]3CCNC3
Molecular Formula
C11H18N4O7S
Molecular Weight
350.35
References & Citations
[1]Andrew M King, et al. Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins. ACS Chem Biol. 2016 Apr 15;11 (4) :864-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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