IMD-biphenylC

• Description :

  IMD-biphenylC is a novel imidazoquinolinone-NF-κB immunomodulator dimer that inhibits tumor proliferation while induces low systemic inflammation and reduces adjuvant toxicity.

• UNSPSC :

  12352005

• Target :

  NF-κB

• Type :

  Reference compound

• Related Pathways :

  NF-κB

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/imd-biphenylc.html

• Solubility :

  10 mM in DMSO

• Smiles :

  NC1=NC(C=CC=C2)=C2C3=C1N=C(CCCC)N3CC4=CC=C(CNC(C5=CC(C6=CC=C(O)C=C6)=CC=C5O)=O)C=C4

• Molecular Formula :

  C35H33N5O3

• Molecular Weight :

  571.67

• References & Citations :

  [1]Kimani FW, et al. Improving the Adjuvanticity of Small Molecule Immune Potentiators Using Covalently Linked NF-κB Modulators. ACS Med Chem Lett. 2021 Aug 26;12 (9) :1441-1448.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  NF-κB

• CAS Number :

  [2928463-42-5]