5-HT7R antagonist 1

5-HT7R antagonist 1

• CAS Number: 2759919-13-4
• UNSPSC Description: 5-HT7R antagonist 1 is a G protein-biased antagonist against 5-HT7R (Ki = 6.5 nM).
• Target Antigen: G protein-coupled Bile Acid Receptor 1
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/5-ht7r-antagonist-1.html
• Solubility: 10 mM in DMSO
• Smiles: ClC1=CC(C2=NNC=C2N3CCCNCC3)=CC=C1.Cl
• Molecular Weight: 313.23
• References & Citations: [1]Kwag R, et al. Discovery of G Protein-Biased Antagonists against 5-HT7R. J Med Chem. 2021 Sep 23;64(18):13766-13779.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported