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MEK4 inhibitor-2

CAT: 0804-HY-139639Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139639Size:1 Each
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Description
MEK4 inhibitor-2 is a novel MEK4 inhibitor against pancreatic adenocarcinoma with an IC50 value of 83 nM.
CAS Number
2833643-78-8
UNSPSC
12352005
Target
MEK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mek4-inhibitor-2.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C(C2=CC=CC(S(=O)(NC3=CC=C(C(N)=O)C=C3)=O)=C2)=NN4)C4=C1
Molecular Formula
C20H15FN4O3S
Molecular Weight
410.42
References & Citations
[1]Kwong AJ, et al. Rational Design, Optimization, and Biological Evaluation of Novel MEK4 Inhibitors against Pancreatic Adenocarcinoma. ACS Med Chem Lett. 2021 Sep 15;12 (10) :1559-1567.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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