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Pioglitazone-d4

CAT: 0804-HY-13956SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13956SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pioglitazone-d4 is a deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1].
CAS Number
1134163-29-3
Product Name Alternative
U 72107-d4
UNSPSC
12352005
Target
Ferroptosis; PPAR
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Purity
99.34
Solubility
10 mM in DMSO|DMF : ≥ 2.5mg/mL|DMSO : ≥ 2.5mg/mL
Smiles
O=C(N1)SC(CC2=C([2H])C([2H])=C(OCCC3=NC=C(CC)C=C3)C([2H])=C2[2H])C1=O
Molecular Formula
C19H16D4N2O3S
Molecular Weight
360.46
References & Citations
[1]Kuwabara K, et al. A novel selective peroxisome proliferator-activated receptor alpha agonist, 2-methyl-c-5-[4-[5-methyl-2- (4-methylphenyl) -4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic acid (NS-220), potently decreases plasma triglyceride and glucose leve
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
Launched

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T12479-01Pioglitazone-d4
TRC-P469996-10MG(±)-Pioglitazone-d4 (phenyl-d4)
CS-T-84109Pioglitazone-d4 (ethyl-d4)
CS-O-02741Pioglitazone-d4 (Phenyl-d4)
sc-355945Pioglitazone - Labeled d4
TMIJ-0093-01Keto Pioglitazone-d4
462656Pioglitazone-d4 (aryl)
462655Pioglitazone-d4 Hydrochloride
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