Thalidomide-4-C3-NH2 (hydrochloride)

CAT:

804-HY-139545

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CAS Number: 2357110-84-8
UNSPSC Description: Thalidomide-4-C3-NH2 hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-C3-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs[1].
Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: Apoptosis;Autophagy;PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/thalidomide-4-c3-nh2-hydrochloride.html
Solubility: 10 mM in DMSO
Smiles: O=C1NC(C(CC1)N2C(C3=CC=C(CCCN)C=C3C2=O)=O)=O.Cl
Molecular Weight: 351.78
References & Citations: [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-994.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-139545	Thalidomide-4-C3-NH2 (hydrochloride)
HY-138847A	Thalidomide-4-O-C3-NH2 (hydrochloride)
HY-149560-02	Thalidomide-5-O-C3-NH2 (hydrochloride)
HY-138850A	Thalidomide-NH-amido-C3-NH2 (hydrochloride)
HY-149560-01	Thalidomide-5-O-C3-NH2 (hydrochloride)
HY-138847	Thalidomide-O-C3-NH2
HY-138850	Thalidomide-NH-amido-C3-NH2
HY-130948B-01	Thalidomide-4-O-C4-NH2 (hydrochloride)
HY-130949B-02	Thalidomide-4-O-C7-NH2 (hydrochloride)
HY-130963B-02	Thalidomide-4-O-C10-NH2 (hydrochloride)

Cat	Name
MBS5800274	Thalidomide-4-C3-NH2 hydrochloride
T39894-10mg	Thalidomide-4-C3-NH2 hydrochloride
T39894-50mg	Thalidomide-4-C3-NH2 hydrochloride
T39894-1g	Thalidomide-4-C3-NH2 hydrochloride
T39894-1mg	Thalidomide-4-C3-NH2 hydrochloride
T39894-5mg	Thalidomide-4-C3-NH2 hydrochloride
MBS5819621	Thalidomide-5-O-C3-NH2 hydrochloride
T39426-1g	Thalidomide-O-amido-C3-NH2
T39426-10mg	Thalidomide-O-amido-C3-NH2
T39426-1mg	Thalidomide-O-amido-C3-NH2