Pomalidomide-5-O-CH3

Pomalidomide-5-O-CH3

• CAS Number: 1547163-02-9
• UNSPSC Description: Pomalidomide-5-O-CH3 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-O-CH3 can be connected to the ligand for protein by a linker to form PROTAC[1].
• Target Antigen: Ligands for E3 Ligase
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pomalidomide-5-o-ch3.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=CC=C(C(N)=C2C(N1C3C(NC(CC3)=O)=O)=O)OC
• Molecular Weight: 303.27
• References & Citations: [1]Andrew J. Phillips, et al. Bromodomain targeting degronimers for target protein degradation. WO2017197056A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported