Thalidomide 4'-oxyacetamide-C1-PEG3-C3-amine (hydrochloride)

Thalidomide 4'-oxyacetamide-C1-PEG3-C3-amine (hydrochloride)

• CAS Number: 2564466-93-7
• UNSPSC Description: Thalidomide 4'-oxyacetamide-C1-PEG3-C3-amine hydrochloride is a functionalized cereblon ligand for PROTAC research and development with terminal amine ready for conjugation to a target protein ligand[1].
• Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy;PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/thalidomide-4-oxyacetamide-c1-peg3-c3-amine-hydrochloride.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(COC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)NCCCOCCOCCOCCCN.Cl
• Molecular Weight: 571.02
• References & Citations: [1]Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported