S-2E

• Description :

  S-2E is an orally active and noncompetitive HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. S-2E has an anti-hyperlipidemic action. S-2E has the potential for familial hypercholesterolemia and mixed hyperlipidemia research[1][2].

• UNSPSC :

  12352005

• Target :

  Acetyl-CoA Carboxylase; HMG-CoA Reductase (HMGCR)

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/s-2e.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N(C2=CC=C(C=C2)C(C)(C)C)C[C@H](C1)COC3=CC=C(C=C3)C(O)=O

• Molecular Formula :

  C22H25NO4

• Molecular Weight :

  367.44

• References & Citations :

  [1]Koichi Ohmori, et al. Anti-hyperlipidemic action of a newly synthesized benzoic acid derivative, S-2E. Eur J Pharmacol. 2003 Jun 13;471 (1) :69-76. |[2]K Ohmori, et al. Effects of a novel antihyperlipidemic agent, S-2E, on the blood lipid abnormalities in homozygous WHHL rabbits. Metabolism. 2004 May;53 (5) :680-5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [155730-92-0]