ACAT-IN-4 (hydrochloride)

ACAT-IN-4 (hydrochloride)

• CAS Number: 199984-46-8
• UNSPSC Description: ACAT-IN-4 hydrochloride (Example 208) is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor. ACAT-IN-4 hydrochloride inhibits NF-κB mediated transcription[1].
• Target Antigen: Acyltransferase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/acat-in-4-hydrochloride.html
• Solubility: 10 mM in DMSO
• Smiles: O=S(OC1=C(C(C)C)C=C(OCCCN)C=C1C(C)C)(NC(CC2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)=O)=O.[H]Cl
• Molecular Weight: 611.28
• References & Citations: [1]Joseph Anthony Cornicelli, et al. Sulfonylaminocarbonyl derivatives for the treatment of nuclear factor-kappa B mediated diseases and disorders. EP1236468A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported