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ACAT-IN-9

CAT: 0804-HY-139026Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139026Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ACAT-IN-9 is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor extracted from patent EP1236468A1, example 207. ACAT-IN-9 inhibits NF-κB mediated transcription[1].
CAS Number
199984-40-2
UNSPSC
12352005
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/acat-in-9.html
Solubility
10 mM in DMSO
Smiles
O=S(OC1=C(C(C)C)C=C(NC(C(C)(N)C)=O)C=C1C(C)C)(NC(CC2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)=O)=O
Molecular Formula
C33H51N3O5S
Molecular Weight
601.84
References & Citations
[1] Joseph Anthony Cornicelli, et al. Sulfonylaminocarbonyl derivatives for the treatment of nuclear factor-kappa B mediated diseases and disorders. EP1236468A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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