TLR7/8 agonist 4 hydroxy-PEG10-acid (hydrochloride)

• UNSPSC Description:

  TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a agent-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the cleavable ADC linker hydroxy-PEG10-acid (HY-133307)[1].

• Target Antigen:

  Drug-Linker Conjugates for ADC

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tlr7-8-agonist-4-hydroxy-peg10-acid-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCC(NC1=C2C(C=CC(N(CC3)CCN3CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=C2)=N4)=NC1=C4N.[H]Cl

• Molecular Weight:

  873.47

• References & Citations:

  [1]Shelley Erin ACKERMAN, et al. Immunoconjugates targeting her2. WO2020190725A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2388520-36-1