Folate-PEG3-amine

• Description:

  Folate-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

• UNSPSC:

  12352203

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/folate-peg3-amine.html

• Purity:

  99.69

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  O=C(O)[C@@H](NC(C1=CC=C(NCC2=CN=C3NC(N)=NC(C3=N2)=O)C=C1)=O)CCC(NCCOCCOCCOCCN)=O

• Molecular Formula:

  C27H37N9O8

• Molecular Weight:

  615.64

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Cleavable Linker

• CAS Number:

  [710323-40-3]