Folate-PEG3-alkyne

• UNSPSC Description:

  Folate-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Folate-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/folate-peg3-alkyne.html

• Smiles:

  NC(NC1=O)=NC2=C1N=C(C=N2)CNC3=CC=C(C(N[C@@H](CCC(NCCOCCOCCOCC#C)=O)C(O)=O)=O)C=C3

• Molecular Weight:

  610.62

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Room temperature

• CAS Number:

  1245285-73-7