N- (2-Hydroxyethyl) oxamic acid

• Description:

  N- (2-hydroxyethyl) -oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria[1][2].

• UNSPSC:

  12352211

• Hazard Statement:

  H302-H312-H332

• Target:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/n-2-hydroxyethyl-oxamic-acid.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)C(NCCO)=O

• Molecular Formula:

  C4H7NO4

• Molecular Weight:

  133.10

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

• References & Citations:

  [1]Koch RL, et al. The anaerobic metabolism of metronidazole forms N- (2-hydroxyethyl) -oxamic acid. J Pharmacol Exp Ther. 1979;208 (3) :406-410.|[2]Freeman CD, et al. Metronidazole. A therapeutic review and update. Drugs. 1997;54 (5) :679-708.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [5270-73-5]