Clezutoclax

CAT: 0804-HY-137774Size: 1 EachDry Ice: NoHazardous: No

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Description

Clezutoclax is a agent-linker conjugate for ADC . Clezutoclax can be used in the synthesis of antibody-drug conjugates (ADCs) [1].

CAS Number

1949843-71-3

UNSPSC

12352005

Target

Drug-Linker Conjugates for ADC

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/clezutoclax.html

Solubility

10 mM in DMSO

Smiles

O=C(OCC(C=CC(NC([C@H](C)NC([C@H](C(C)C)NC(CN(C1=O)[C@@H](C[C@@H]1N(C2=O)C(C=C2)=O)COCC[S](=O)(O)=O)=O)=O)=O)=C3)=C3CC[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)C(O)=O)N(CC[C@H](O)CO)CCO[C@](C5)(C6)C[C@@](C[C@@]6(C7)C)(C[C@]57C)CN8C(C)=C(C(C=CC(N(CCC9=CC=C%10)CC9=C%10C(NC%11=NC%12=CC=CC=C%12S%11)=O)=N%13)=C%13C(O)=O)C=N8

Molecular Formula

C83H102N12O24S2

Molecular Weight

1715.89

References & Citations

[1]Boni V, et al. The Resurgence of Antibody Drug Conjugates in Cancer Therapeutics: Novel Targets and Payloads. Am Soc Clin Oncol Educ Book. 2020 Mar;40:1-17.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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