10-Formyl-7,8-dihydrofolic acid

CAT:

804-HY-137129

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CAS Number: 28459-40-7
UNSPSC Description: 10-Formyl-7,8-dihydrofolic acid is a substrate for mammalian aminoimidazolecarboxamide ribotide transformylase (EC 2.1.2.3). 10-Formyl-7,8-dihydrofolic acid also is a metabolite of 10-HCO-H4folate[1][2].
Target Antigen: Endogenous Metabolite
Type: Reference compound
Related Pathways: Metabolic Enzyme/Protease
Applications: Metabolism-sugar/lipid metabolism
Field of Research: Metabolic Disease
Assay Protocol: https://www.medchemexpress.com/10-formyl-7-8-dihydrofolic-acid.html
Solubility: 10 mM in DMSO
Smiles: O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(N(CC2=NC3=C(N=C(N)NC3=O)NC2)C=O)C=C1)=O
Molecular Weight: 471.42
References & Citations: [1]Baggott JE, et al. Iron compounds catalyze the oxidation of 10-formyl-5,6,7,8 tetrahydrofolic acid to 10-formyl-7,8 dihydrofolic acid. J Inorg Biochem. 1998 Sep;71(3-4):181-7.|[2]Baggott JE, et al. Metabolism of 10-formyldihydrofolate in humans. Biomed Pharmacother. 2001 Oct;55(8):454-7.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-137129	10-Formyl-7,8-dihydrofolic acid
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