10-Formyl-7,8-dihydrofolic acid

• UNSPSC Description:

  10-Formyl-7,8-dihydrofolic acid is a substrate for mammalian aminoimidazolecarboxamide ribotide transformylase (EC 2.1.2.3). 10-Formyl-7,8-dihydrofolic acid also is a metabolite of 10-HCO-H4folate[1][2].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/10-formyl-7-8-dihydrofolic-acid.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(N(CC2=NC3=C(N=C(N)NC3=O)NC2)C=O)C=C1)=O

• Molecular Weight:

  471.42

• References & Citations:

  [1]Baggott JE, et al. Iron compounds catalyze the oxidation of 10-formyl-5,6,7,8 tetrahydrofolic acid to 10-formyl-7,8 dihydrofolic acid. J Inorg Biochem. 1998 Sep;71(3-4):181-7.|[2]Baggott JE, et al. Metabolism of 10-formyldihydrofolate in humans. Biomed Pharmacother. 2001 Oct;55(8):454-7.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  28459-40-7