Levamisole-d5 (hydrochloride)

• UNSPSC Description:

  Levamisole-d5 (hydrochloride) is the deuterium labeled Levamisole hydrochloride. Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV[1][2].

• Target Antigen:

  HSV; Isotope-Labeled Compounds; Parasite

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection;Others

• Field of Research:

  Infection; Neurological Disease

• Solubility:

  10 mM in DMSO

• Smiles:

  [2H]C1=C([2H])C([2H])=C([2H])C([2H])=C1[C@@]2([H])CN3C(SCC3)=N2.Cl

• Molecular Weight:

  245.78

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Centers for Disease Control and Prevention (CDC). Agranulocytosis associated with cocaine use - four States, March 2008-November 2009.MMWR Morb Mortal Wkly Rep. 2009 Dec 18;58(49):1381-5.|[3]Zhu NY, et al. Agranulocytosis after consumption of cocaine adulterated with levamisole. Ann Intern Med. 2009 Feb 17;150(4):287-9.|[4]Van Belle H. Alkaline phosphatase. I. Kinetics and inhibition by levamisole of purified isoenzymes from humans. Clin Chem. 1976 Jul;22(7):972-6.|[5]Friedlaender MH, et al. The treatment of herpetic reinfection with levamisole. Am J Ophthalmol. 1978 Aug;86(2):245-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1246819-64-6