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Tenofovir diphosphate

CAT: 0804-HY-136548Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-136548Size:1 Each
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Description
Tenofovir diphosphate is an antiretroviral agent. Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase DNA (Ki = 1.55 μM) and RNA (Ki = 0.022 μM) . Tenofovir diphosphate can be used for the research of AIDS[1].
CAS Number
166403-66-3
Product Name Alternative
TFV-DP
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tenofovir-diphosphate.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](OC[P](O[P](O[P](O)(O)=O)(O)=O)(O)=O)CN1C2=NC=NC(N)=C2N=C1
Molecular Formula
C9H16N5O10P3
Molecular Weight
447.17
References & Citations
[1]Gabriel Birkus, et al. Tenofovir Diphosphate Is a Poor Substrate and a Weak Inhibitor of Rat DNA Polymerases Alpha, Delta, and epsilon. Antimicrob Agents Chemother. 2002 May;46 (5) :1610-3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported