Polyoxin D

• Description :

  Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, is a potent chitin synthetase inhibitor[1][2].

• Product Name Alternative :

  Polyoxorim

• UNSPSC :

  12352005

• Target :

  Antibiotic; Fungal

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/polyoxin-d.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(C(C(N1)=O)=CN([C@H]2[C@H](O)[C@H](O)[C@@H]([C@H](NC([C@H]([C@@H]([C@H](COC(N)=O)O)O)N)=O)C(O)=O)O2)C1=O)=O

• Molecular Formula :

  C17H23N5O14

• Molecular Weight :

  521.39

• References & Citations :

  [1]B Bowers, et al. Effect of polyoxin D on chitin synthesis and septum formation in Saccharomyces cerevisiae. J Bacteriol. 1974 Aug;119 (2) :564-75.|[2]J M Becker, et al. Polyoxin D inhibits growth of zoopathogenic fungi. Antimicrob Agents Chemother. 1983 Jun;23 (6) :926-9.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [22976-86-9]