Polyoxin D

• Description:

  Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, is a potent chitin synthetase inhibitor[1][2].

• Product Name Alternative:

  Polyoxorim

• UNSPSC:

  12352005

• Target:

  Antibiotic; Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/polyoxin-d.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C(C(N1)=O)=CN([C@H]2[C@H](O)[C@H](O)[C@@H]([C@H](NC([C@H]([C@@H]([C@H](COC(N)=O)O)O)N)=O)C(O)=O)O2)C1=O)=O

• Molecular Formula:

  C17H23N5O14

• Molecular Weight:

  521.39

• References & Citations:

  [1]B Bowers, et al. Effect of polyoxin D on chitin synthesis and septum formation in Saccharomyces cerevisiae. J Bacteriol. 1974 Aug;119 (2) :564-75.|[2]J M Becker, et al. Polyoxin D inhibits growth of zoopathogenic fungi. Antimicrob Agents Chemother. 1983 Jun;23 (6) :926-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [22976-86-9]