N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol

CAT:

804-HY-136130

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UNSPSC Description: N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen: ADC Linker
Type: ADC Related
Related Pathways: Antibody-drug Conjugate/ADC Related
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/n-n-bis-peg2-alkyne-n-amido-peg2-thiol.html
Solubility: 10 mM in DMSO
Smiles: O=C(CCOCCOCCS)N(CCOCCOCC#C)CCOCCOCC#C
Molecular Weight: 445.57
References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-136130	N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol
HY-136129	N,N-Bis(PEG2-N3)-N-amido-PEG2-thiol
HY-140083	Propargyl-PEG2-N-bis(PEG2)
HY-140093-04	N-(PEG2-Boc)-N-bis(PEG2-propargyl)
HY-140093-03	N-(PEG2-Boc)-N-bis(PEG2-propargyl)
HY-140093-02	N-(PEG2-Boc)-N-bis(PEG2-propargyl)
HY-140093-01	N-(PEG2-Boc)-N-bis(PEG2-propargyl)
HY-140085	N-(PEG2-C2-acid)-N-bis(PEG2-propargyl)
HY-140586-02	N-Benzyl-N-bis-PEG2
HY-140586-01	N-Benzyl-N-bis-PEG2