N-(PEG2-Boc)-N-bis(PEG2-propargyl)

N-(PEG2-Boc)-N-bis(PEG2-propargyl)

• CAS Number: 2100306-69-0
• UNSPSC Description: N-(PEG2-Boc)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(PEG2-Boc)-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n-peg2-boc-n-bis-peg2-propargyl.html
• Solubility: 10 mM in DMSO
• Smiles: C#CCOCCOCCN(CCOCCOCC#C)CCOCCOCCC(OC(C)(C)C)=O
• Molecular Weight: 485.61
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported