DBCO-NH-PEG7-C2-NHS ester

DBCO-NH-PEG7-C2-NHS ester

• UNSPSC Description: DBCO-NH-PEG7-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-NH-PEG7-C2-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dbco-nh-peg7-c2-nhs-ester.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(CCNC(CCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O)N(C2)C3=C(C=CC=C3)C#CC4=C2C=CC=C4
• Molecular Weight: 781.85
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported