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Betamethasone acetate

CAT: 0804-HY-13570B-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13570B-01Size:1 mg
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Description
Betamethasone acetate is a glucocorticoid with prenatal application for preventing respiratory distress syndrome (RDS) in premature infants. Betamethasone acetate exhibits dose-dependent effects on somatic and brain development in offspring when administered prenatally to pregnant rats. Betamethasone acetate can be used for the study of antenatal intervention[1][2].
CAS Number
987-24-6
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/betamethasone-acetate.html
Purity
99.38
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](C[C@H](C)[C@]2(O)C(COC(C)=O)=O)([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](O)C1)=O
Molecular Formula
C24H31FO6
Molecular Weight
434.50
Precautions
H302, H315, H319, H335
References & Citations
[1]Schmidt AF, et al. Low-dose betamethasone-acetate for fetal lung maturation in preterm sheep. Am J Obstet Gynecol. 2018 Jan;218 (1) :132.e1-132.e9.|[2]Scheepens A, et al. A single course of prenatal betamethasone in the rat alters postnatal brain cell proliferation but not apoptosis. J Physiol. 2003 Oct 1;552 (Pt 1) :163-75.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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