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DC4

CAT: 0804-HY-135125Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-135125Size:1 Each
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Description
DC4, an ADC cytotoxin, can be used in the synthesis of antibody-drug conjugate (ADC) . DC4 can be used for the targeted treatment of cancer[1].
CAS Number
615538-48-2
UNSPSC
12352203
Target
ADC Payload
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dc4.html
Solubility
10 mM in DMSO
Smiles
O=C(C(N1)=CC2=C1C=CC(NC(CCS)=O)=C2)NC3=CC4=C(NC(C(N5C[C@@H](CCl)C6=C5C=C(OP(O)(O)=O)C7=CC=CC=C67)=O)=C4)C=C3
Molecular Formula
C34H29ClN5O7PS
Molecular Weight
718.12
References & Citations
[1]Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55 (2) :766-82.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported

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