10-DEBC

• Description :

  10-DEBC is a selective Akt inhibitor. 10-DEBC shows strong inhibitory activity against Moloney murine leukemia virus (Pim) kinase-1 (IC50=1.28 μM) [1].

• UNSPSC :

  12352005

• Target :

  Pim

• Type :

  Reference compound

• Related Pathways :

  JAK/STAT Signaling

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/10-debc.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CCN(CC)CCCCN1C2=C(C=CC=C2)OC3=CC=C(Cl)C=C13

• Molecular Formula :

  C20H25ClN2O

• Molecular Weight :

  344.88

• References & Citations :

  [1]Li, W., et al. More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors. Med. Chem. Commun. 2014;5 (4) :507–511.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [201788-90-1]