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10-DEBC

CAT: 0804-HY-133850Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-133850Size:1 Each
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Description
10-DEBC is a selective Akt inhibitor. 10-DEBC shows strong inhibitory activity against Moloney murine leukemia virus (Pim) kinase-1 (IC50=1.28 μM) [1].
CAS Number
201788-90-1
UNSPSC
12352005
Target
Pim
Type
Reference compound
Related Pathways
JAK/STAT Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/10-debc.html
Solubility
10 mM in DMSO
Smiles
CCN(CC)CCCCN1C2=C(C=CC=C2)OC3=CC=C(Cl)C=C13
Molecular Formula
C20H25ClN2O
Molecular Weight
344.88
References & Citations
[1]Li, W., et al. More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors. Med. Chem. Commun. 2014;5 (4) :507–511.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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