10-DEBC

• Description:

  10-DEBC is a selective Akt inhibitor. 10-DEBC shows strong inhibitory activity against Moloney murine leukemia virus (Pim) kinase-1 (IC50=1.28 μM) [1].

• UNSPSC:

  12352005

• Target:

  Pim

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/10-debc.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCN(CC)CCCCN1C2=C(C=CC=C2)OC3=CC=C(Cl)C=C13

• Molecular Formula:

  C20H25ClN2O

• Molecular Weight:

  344.88

• References & Citations:

  [1]Li, W., et al. More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors. Med. Chem. Commun. 2014;5 (4) :507–511.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [201788-90-1]