Heliotrine N-oxide

Heliotrine N-oxide

• CAS Number: 6209-65-0
• UNSPSC Description: Heliotrine N-oxide is the corresponding PA (pyrrolizidine alkaloid) N-oxide of Heliotrine (HY-126128). Heliotrine N-oxide leads to the formation of pyrrolic DNA adducts and potential initiation of PA-induced liver tumors in vivo[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/heliotrine-n-oxide.html
• Solubility: 10 mM in DMSO
• Smiles: [O-][N+]1(CC[C@@H]2O)[C@]2([H])C(COC([C@@](C(C)C)(O)[C@@H](C)OC)=O)=CC1
• Molecular Weight: 329.39
• References & Citations: [1]Xiaobo He, et al. Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides. J Food Drug Anal. 2017 Oct;25(4):984-991.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported