Methyltetrazine-PEG4-SSPy

Methyltetrazine-PEG4-SSPy

• UNSPSC Description: Methyltetrazine-PEG4-SSPy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Methyltetrazine-PEG4-SSPy is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/methyltetrazine-peg4-sspy.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=NN=C(C2=CC=C(CNC(CCOCCOCCOCCOCCNC(CCSSC3=CC=CC=N3)=O)=O)C=C2)N=N1
• Molecular Weight: 645.79
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported