(S,R,S)-AHPC-C8-NH2 (dihydrochloride)

(S,R,S)-AHPC-C8-NH2 (dihydrochloride)

• CAS Number: 2341796-80-1
• UNSPSC Description: (S,R,S)-AHPC-C8-NH2 dihydrochloride (VH032-C8-NH2 dihydrochloride) is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the VH032 based VHL ligand and a linker used for?AKT?PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-c8-nh2-dihydrochloride.html
• Solubility: 10 mM in DMSO
• Smiles: [H]Cl.[H]Cl.O=C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(CCCCCCCCN)=O
• Molecular Weight: 658.72
• References & Citations: [1][1].Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported