Iodo-PEG12-NHS ester

• Description:

  Iodo-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/iodo-peg12-nhs-ester.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ICCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC (ON1C (CCC1=O) =O) =O

• Molecular Formula:

  C31H56INO16

• Molecular Weight:

  825.68

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]"An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. "

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Alkyl/ether Linkers; PEG Linkers