Hydroxy-PEG16-acid

• Description:

  Hydroxy-PEG16-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• Product Name Alternative:

  HO-PEG16-CH2CH2COOH

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hydroxy-peg16-acid.html

• Purity:

  99.81

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

• Molecular Formula:

  C35H70O19

• Molecular Weight:

  794.92

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PEG Linkers