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Guajadial C

CAT: 0804-HY-133219Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-133219Size:1 Each
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Description
Guajadial C is a Top1 catalytic inhibitor that delays Top1 poison-mediated DNA damage. Guajadial C shows cytotoxicity against cancer cells[1].
CAS Number
1529775-02-7
UNSPSC
12352005
Target
Topoisomerase
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/guajadial-c.html
Solubility
10 mM in DMSO
Smiles
O=CC1=C(O)C(C=O)=C2C([C@@H](C3=CC=CC=C3)C[C@@]4(C=C5[C@H](C(C)C)CC[C@@H](C)[C@@]5([H])CC4)O2)=C1O
Molecular Formula
C30H34O5
Molecular Weight
474.59
References & Citations
[1]Qin XJ, et al. Meroterpenoids with Antitumor Activities from Guava (Psidium guajava) . J Agric Food Chem. 2017 Jun 21;65 (24) :4993-4999.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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