Oseltamivir-d3 (hydrochloride)

Oseltamivir-d3 (hydrochloride)

• UNSPSC Description: Oseltamivir-d3 hydrochloride is the deuterium-labeled Oseltamivir (HY-13317)[1]. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[2].
• Target Antigen: Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Others
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Solubility: 10 mM in DMSO
• Smiles: CCOC(C(C[C@@H]([C@H]1NC(C([2H])([2H])[2H])=O)N)=C[C@H]1OC(CC)CC)=O.Cl
• Molecular Weight: 351.88
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported