hDDAH-1-IN-1 (TFA)

hDDAH-1-IN-1 (TFA)

• CAS Number: 1229238-70-3
• UNSPSC Description: hDDAH-1-IN-1 TFA (compound 8a) is a potent and selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), with a Ki of 18 μM[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/hddah-1-in-1-tfa.html
• Solubility: 10 mM in DMSO
• Smiles: N=C(NCCOC)NCCCCN.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
• Molecular Weight: 416.32
• References & Citations: [1]Lunk I, et al. Discovery of N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1). J Med Chem. 2019 Dec 31.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported