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FFN270 (hydrochloride)

CAT: 0804-HY-131007Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-131007Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FFN270 hydrochloride, a fluorescent tracer of norepinephrine, is a fluorescent substrate of the norepinephrine and vesicular monoamine transporters. FFN270 hydrochloride exhibits two resolved absorption/excitation maxima depending on solvent pH (FFN270 ex: 320 nm or 365 nm, em: 475 nm) and can function as ratiometric fluorescent pH-sensors[1].
CAS Number
2341841-05-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ffn270-hydrochloride.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C1C(CCN)=CC2=CC=C(O)C(F)=C2O1.[H]Cl
Molecular Formula
C11H11ClFNO3
Molecular Weight
259.66
Precautions
H302, H315, H319, H335
References & Citations
[1]Matthew Dunn, et al. Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo. Nat Commun. 2018 Jul 19;9 (1) :2838.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

FFN270 hydrochloride
CAS Number2341841-05-0
PubChem CID138991779
IUPAC Name3-(2-aminoethyl)-8-fluoro-7-hydroxychromen-2-one;hydrochloride
Molecular FormulaC11H11ClFNO3
Molecular Weight259.66
Topological Polar Surface Area72.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count17
Formal Charge0
Complexity318
SMILES
C1=CC(=C(C2=C1C=C(C(=O)O2)CCN)F)O.Cl
InChI
InChI=1S/C11H10FNO3.ClH/c12-9-8(14)2-1-6-5-7(3-4-13)11(15)16-10(6)9;/h1-2,5,14H,3-4,13H2;1H
InChIKey
DMAWKEXYKIZCQD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of FFN270 hydrochloride
CAS: 2341841-05-0
CID: 138991779
Formula: C11H11ClFNO3
MW: 259.66
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight259.66
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass259.0411491
Monoisotopic Mass259.0411491
Topological Polar Surface Area72.6 Ų
Heavy Atom Count17
Formal Charge0
Complexity318
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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