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Bromoacetamide-PEG3-propargyl

CAT: 0804-HY-130942-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-130942-01Size:5 mg
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Description
Bromoacetamide-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromoacetamide-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
932741-11-2
UNSPSC
12352211
Hazard Statement
H302, H314
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bromoacetamide-peg3-propargyl.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCOCC#C)CBr
Molecular Formula
C11H18BrNO4
Molecular Weight
308.17
Precautions
H302, H314
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

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