Bis-propargyl-PEG3

• UNSPSC Description:

  Bis-propargyl-PEG3 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG3 is used in the synthesis of zinc-dipicolylamine (ZnDPA) complexes with antiplasmodial activity[1] [2]. Bis-propargyl-PEG3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer; Infection

• Assay Protocol:

  https://www.medchemexpress.com/bis-propargyl-peg3.html

• Smiles:

  C#CCOCCOCCOCCOCC#C

• Molecular Weight:

  226.27

• References & Citations:

  [1]Pearlie BURNETTE, et al. Dimeric immuno-modulatory compounds against cereblon-based mechanisms. WO2020014489A2.|[2]Rice DR, et al. Antiplasmodial activity of targeted zinc(II)-dipicolylamine complexes. Bioorg Med Chem. 2017 May 15;25(10):2754-2760.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  126422-58-0