Pyracrenic acid

• Description:

  Pyracrenic acid is an elastase inhibitor (IC50 = 2.42 µM), can be obtained from the bark of Pyracantha crenulata. Pyracrenic acid has DPPH free radical scavenging activity and anti-inflammatory activity[1][2].

• UNSPSC:

  12352005

• Target:

  Elastase

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/pyracrenic-acid.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1(C)[C@@H](OC(/C=C/C2=CC=C(O)C(O)=C2)=O)CC[C@]3(C)[C@@]4([H])CC[C@]5([H])[C@@]6([H])[C@H](C(C)=C)CC[C@@](C(O)=O)6CC[C@](C)5[C@@](C)4CC[C@@]13[H]

• Molecular Formula:

  C39H54O6

• Molecular Weight:

  618.84

• References & Citations:

  [1]Otsuka H, et al. Studies on anti-inflammatory agents. V. A new anti-inflammatory constituent of Pyracantha crenulata roem. Chem Pharm Bull (Tokyo) . 1981 Nov;29 (11) :3099-104. |[2]Kim J H, et al. Compounds with elastase inhibition and free radical scavenging activities from Callistemon lanceolatus. J Med Plants Res. 2009, 3 (11) : 914-920.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [80832-44-6]