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LY125180

CAT: 0804-HY-129682Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129682Size:1 Each
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Description
LY125180 is a competitive inhibitor of the uptake of serotonin and norepinephrine by cortical synaptosomes and of dopamine by striatal synaptosomes, with Ki values of 0.06, 2.2 and 2.5 μM respectively[1].
CAS Number
74515-39-2
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly125180.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(OCCC(C2=CC=CC=C2)N(C)C)C=C1.[H]Cl
Molecular Formula
C18H24ClNO
Molecular Weight
305.84
References & Citations
[1]Wong DT, et al. N, N-Dimethyl-alpha-[2- (p-tolyloxy) ethyl]benzylamine hydrochloride (LY125180) . Effects on serotonin uptake and serotonin synthesis in rat brain in vitro and in vivo. Biochem Pharmacol. 1980 Mar 15;29 (6) :935-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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