Amidepsine D

• Description :

  Amidepsine D is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity[1].

• CAS Number :

  [79786-34-8]

• UNSPSC :

  12352005

• Hazard Statement :

  H315-H319-H335

• Target :

  Acyltransferase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/amidepsine-d.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(OC1=CC(C)=C(C(O)=O)C(O)=C1)C2=C(C)C=C(OC(C3=C(C)C=C(OC)C=C3OC)=O)C=C2O

• Molecular Formula :

  C26H24O10

• Molecular Weight :

  496.46

• Precautions :

  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Tomoda H, et al. Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties. J Antibiot (Tokyo) . 1995 Sep;48 (9) :937-41.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported