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AZD5213

CAT: 0804-HY-129250Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129250Size:1 Each
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Description
AZD5213 is a selective and competitive human H3 receptor antagonist with a pKi value of 9.3 for hH3R. AZD5213 can be used for the research of sleep and cognitive regulation[1][2].
CAS Number
1119807-02-1
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/azd5213.html
Solubility
10 mM in DMSO
Smiles
O=C(N)C1=CC=C([C@@H]2[C@@H](C(N3CCN(C4CCC4)CC3)=O)C2)C=C1
Molecular Formula
C19H25N3O2
Molecular Weight
327.42
References & Citations
[1]Schou M, et al. Discovery and Preclinical Validation of [ (11) C]AZ13153556, a Novel Probe for the Histamine Type 3 Receptor. ACS Chem Neurosci. 2016 Feb 17;7 (2) :177-84.|[2]Nikolic K, et al. Procognitive properties of drugs with single and multitargeting H3 receptor antagonist activities. CNS Neurosci Ther. 2014 Jul;20 (7) :613-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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