TGFBR1-IN-1

CAT: 0804-HY-129171Size: InquireDry Ice: NoHazardous: No

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CAT#:0804-HY-129171Size:Inquire

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2170830-26-7

UNSPSC Description

TGFBR1-IN-1 is an ALK5 inhibitor extracted from patent WO2018004290A1, Compound 33, has an IC50 of 10-100 nM[1].

Target Antigen

TGF-β Receptor

Type

Reference compound

Related Pathways

TGF-beta/Smad

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tgfbr1-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=NN(C2=NC(C)=CC=C2)C(C3=CC=C4N=CSC4=C3)=C1)NC5=CC=C(O)C=C5

Molecular Weight

427.48

References & Citations

[1]Novel pyrazole derivative as alk5 inhibitor and uses thereof. WO2018004290A1.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

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